The invention relates to a cargo handling system (1) for loading and securing one or more freight containers (C) in a cargo hold (H) of an aircraft (A). The system (1) comprises: a plurality of bracket members (2) configured to be secured to a base or floor of the cargo hold (H); and a plurality of elongate guide members (5), each of which is mounted on and interconnects a number of the bracket members (2) arranged in a row; wherein each guide member (5) forms a restraint or a stop against lateral movement of a freight container (C) loaded in the cargo hold (H). The bracket members (2) include at least one fastening portion (3) configured for tool-less fast-release engagement and locking with a seat track profile in the base or floor (F) of the cargo hold (H). Furthermore, the bracket members (2) typically extend transversely inwards or inboard of the elongate guide members (5).