A real time tire pressure monitoring system and method is disclosed. It includes a sensor measuring a pressure of a first tire and a sensor measuring a pressure of a second tire. The measured pressures are transmitted from the sensors to a processor, and a fusion module is executed on the processor. The fusion module includes a filter module that receives the first tire pressure, determines a leak rate of the first tire, and generates a filter module flag when the leak rate falls below a predetermined leak threshold. The fusion module also includes a comparative module that receives the first and second tire measured pressures, compares the measured pressures, and generates a comparative module flag when a deviation exceeds a predetermined deviation threshold. The fusion module generates a system notification when both the filter module flag and the comparative module flag indicate a pressure leak.