Ancient Australian fossils indicate that the earliest eukaryotes depended on oxygen, providing new evidence that oxygen helped enable the evolution of complex life. Stored in an open-air warehouse in tropical Darwin, Australia, are dozens of trays containing cylindrical cores of rock. They are from drill holes bored hundreds of meters below the surface by mineral [...]
A new study has uncovered an unexpected vulnerability in some of the deadliest cancers. Researchers at UCLA have identified a previously hidden weakness in some of the most aggressive cancers, pointing to a possible new way to attack tumors that have remained difficult to treat. Small cell neuroendocrine cancers can develop in the lungs, prostate, [...]
It came from a creature of the depths. A severed foot that refused to die, regenerating in an act of survival unlike anything we’ve ever seen.
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Category: Biology, Science
Tags: Regeneration, echinoderms, Cells, Ocean
Scientists have identified a new way to supercharge the GLP-1 receptor agonist semaglutide, opening the door to boosting the drug's weight-loss power and helping long-term users push past plateaus that not even this "wonder drug" can circumvent.
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Category: Obesity, Illnesses and conditions, Body and Mind
Tags: National Institutes of Health (NIH), U.S. National…
Researchers investigating a widely used medication have uncovered an unexpected cellular process that may interfere with early brain development. A medication widely used to control epilepsy, migraines, and bipolar disorder has long carried a serious warning for pregnant patients. Valproic acid is known to increase the risk of birth defects, but scientists have struggled to [...]
For more than two decades, giant viruses have unsettled one of biology’s most fundamental boundaries: the line between simple viruses and complex cells. With genomes rivaling some bacteria, and gene sets that resemble those of eukaryotes (cells with membrane-bound nuclei and other internal compartments), they have forced scientists to rethink how cellular complexity may have emerged. A newly…
A newly identified role for the neuronal MPS shows it controls nutrient uptake by acting as a gatekeeper. Its disruption speeds endocytosis and promotes toxic amyloid buildup linked to Alzheimer’s. Brain cells constantly draw in material from the fluid around them, including signaling molecules, nutrients, and even fragments of their own outer membranes. This process, [...]