Semaglutide was linked to greater weight loss and a 15% lower fracture risk in people with type 2 diabetes, raising the possibility of an unexpected bone health benefit. People with type 2 diabetes who took semaglutide experienced greater weight loss and a lower risk of bone fractures than those using several other weight-loss medications, according [...]

People taking popular GLP-1 weight-loss drugs like Ozempic, Wegovy, Mounjaro, and Zepbound may be shedding pounds, but a new study suggests they are also moving less. People with obesity who lost weight while taking popular medications such as Ozempic, Wegovy, Zepbound, and similar drugs became significantly less physically active, according to research presented at ENDO [...]

A surprising study found that cutting out sugar completely may disrupt the gut microbiome and worsen metabolic health. Cutting sugar out of your diet entirely may not be as beneficial as many people assume. New research in mice suggests that completely eliminating sucrose could have unintended effects on gut health and metabolism. The findings were [...]

A major new review says “yo-yo dieting” may not be nearly as harmful as people have been told. Repeated cycles of losing weight and gaining it back, often called “yo-yo dieting” or weight cycling, are frequently described as harmful to health and metabolism. Some experts have even suggested that repeatedly regaining weight may be worse [...]

A new study suggests that the effectiveness of widely used GLP-1 weight-loss drugs may depend strongly on consistent use. Intermittently stopping and restarting popular GLP-1 weight loss drugs such as Ozempic and Wegovy may weaken their impact over time, according to new research from the Perelman School of Medicine at the University of Pennsylvania. In [...]

New research suggests the risks tied to early pregnancy exposure to popular weight loss drugs may not be the same for every patient. New research suggests that early pregnancy exposure to popular weight loss drugs may not carry the same risks for every patient. These medications were linked to a higher risk of preterm birth [...]

Common “forever chemicals” could quietly undermine kids’ bone strength before they even reach adulthood. New research published today (March 17) in the Journal of the Endocrine Society suggests that exposure to per- and polyfluoroalkyl substances (PFAS) early in life could play a role in how children’s bones form during adolescence. PFAS are man-made chemicals commonly [...]

Achieving remission from prediabetes dramatically reduces the risk of heart disease and other major cardiovascular events. Lowering blood sugar levels dramatically reduces the risk of serious heart problems in people with prediabetes. Research from King’s College London, published in The Lancet Diabetes & Endocrinology, shows that restoring blood glucose levels to a normal range, effectively [...]

Nicotine exposure in fathers may quietly reshape their children’s metabolism, hinting at a hidden link to diabetes risk. New research published today (March 12) in the Journal of the Endocrine Society suggests that nicotine exposure in fathers may influence how their offspring process sugar. In a mouse study, scientists found that paternal nicotine intake altered [...]

A new study suggests that a common menopause treatment may influence how effectively certain weight-loss medications work. A new study led by Mayo Clinic reports that postmenopausal women who used menopausal hormone therapy lost significantly more weight while taking tirzepatide, a drug approved by the U.S. Food and Drug Administration to treat overweight and obesity. [...]

A growing body of research suggests the brain plays a central role in diabetic ketoacidosis, opening the possibility of treating type 1 diabetes in an entirely new way. More than 10 years ago, scientists made an unexpected discovery about a life-threatening complication of type 1 diabetes. They found that diabetic ketoacidosis (DKA) could be reversed [...]