New findings indicate that finerenone may help protect kidney function and reduce major health risks in people with chronic kidney disease who do not have diabetes. Chronic kidney disease affects an estimated 800 million people worldwide and is one of the leading causes of kidney failure, cardiovascular complications, and premature death. Yet for many patients [...]

A kidney test result that appears perfectly normal may still reveal hidden danger, according to a major new study involving more than a million adults. Even small differences in kidney function, including values that still fall within the normal range, may reveal who is at greater risk of developing chronic kidney disease. That is the [...]

Unusual fat deposits in domestic cat kidneys may reveal why cats are especially vulnerable to chronic kidney disease. Scientists at the University of Nottingham have identified an unexpected feature of domestic cat biology that could help explain their high risk of chronic kidney disease. Compared with dogs and most other mammals, domestic cats seem to [...]

New research indicates that maintaining meaningful weight loss after starting GLP-1-based therapies could play an important role in reducing the risk of multiple obesity-related diseases. Popular weight loss drugs such as semaglutide (Ozempic, Wegovy, and Rybelsus) and tirzepatide (Mounjaro and Zepbound) may do more than help people lose weight. New research suggests the amount of [...]

A new experimental drug lowered blood pressure and sharply reduced signs of kidney damage in people with chronic kidney disease. Baxdrostat, an investigational pill designed to block production of the hormone aldosterone, showed encouraging results in people facing a difficult and dangerous combination: chronic kidney disease and uncontrolled high blood pressure. In a Phase 2 [...]

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that the Y has little biological importance beyond sex determination. As men age, some of their cells gradually lose the Y chromosome. For a long time, researchers assumed this change had little medical importance because the Y [...]

A monthly infusion may one day replace daily immunosuppressant pills for kidney transplant patients. A kidney transplant can be life-changing, but it usually comes with a lifelong tradeoff: daily immunosuppressant pills that keep the immune system from attacking the donated organ. A new study suggests there may be another path in the future, one that [...]