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Mouse with Severed Spinal Cord Recovers ‘Normal’ Movement After Potentially Revolutionary Treatment

In an impressive early demonstration of a potentially revolutionary technology, biotech engineers in Zurich used micro-sized robots and stem cells to restore normal movement in a mouse whose spinal cord was entirely severed. The tech was also demonstrated in zebrafish, and the engineers behind the demonstration say it brings multiple advantages over existing, similar methods. […]

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Breakthrough for 800 Million Patients? Kidney Disease Drug Shows Powerful New Benefits

New findings indicate that finerenone may help protect kidney function and reduce major health risks in people with chronic kidney disease who do not have diabetes. Chronic kidney disease affects an estimated 800 million people worldwide and is one of the leading causes of kidney failure, cardiovascular complications, and premature death. Yet for many patients [...]

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Staggering Results Show HIV-Transmission Reduced 100% with Twice-Yearly Lenacapavir Injection

A 2-stage trial testing a new and acclaimed HIV-prevention drug has shown almost unthinkable results of no new infections among a sample size of 3,200 participants. Called PURPOSE 1, the aim of the first trial was testing a subcutaneous injection of the drug Lenacapavir given twice a year to people in a high-HIV-incidence country, which […]

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Breast cancer genomic test could spare millions from chemotherapy

BY THE OPTIMIST DAILY EDITORIAL TEAM For decades, high clinical risk and chemotherapy arrived together as a package deal in early breast cancer. A trial presented at the American Society of Clinical Oncology meeting in Chicago on May 30, 2026, is pulling them apart. The OPTIMA trial enrolled more than 4,400 patients across the United […]

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Inside the Trump-backed push to bring AI doctors into American medicine

Washington Post [no paywall]: “The administration is laying the groundwork for chatbots that can diagnose illness and prescribe medicine, but physicians say AI can introduce more problems…Today, chatbots can only legally offer medical guidance with a disclaimer attached: Neither the U.S. Food and Drug Administration, nor any state licensing board, allows a fully autonomous AI ...

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LLRX May 2026 Issue – Articles and Columns

LLRX https://www.llrx.com Trump Administration’s Continued War Against Science, Research, Public Health and the Rule of Law – Part 9 – Sabrina I. Pacifici Tracking hallucination marketing claims from legal tech vendors. Damien Charlotin Deep Coverage – Right now the dominant AI strategy in law is using AI to replace or augment human labor on work ...

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Uber’s Brazen Legal Strategy to Quiet Accident Victims

For years, corporations and insurers have complained that America’s personal injury system is overrun with frivolous claims, shady doctors, and greedy lawyers. Now Uber is trying to turn those complaints into federal racketeering cases.

Over the past two years, the ride-hailing company has filed at least four civil RICO lawsuits around the country accusing plaintiffs’ legal firms and medical…

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A daily pill just doubled survival time for advanced pancreatic cancer

BY THE OPTIMIST DAILY EDITORIAL TEAM In a 500-patient trial at American Society of Clinical Oncology’s (ASCO) annual meeting in Chicago, a daily pill called daraxonrasib doubled average survival time in patients with advanced pancreatic cancer. Those on the drug lived for an average of 13.2 months. Those on standard chemotherapy lived for 6.6 to […]

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Goodbye CPAP? New Pill Shows Major Promise for Sleep Apnea

A large phase 3 clinical trial has revealed promising results for a once-nightly pill designed to treat obstructive sleep apnea by targeting the biological mechanisms that cause airway collapse during sleep. A once-nightly pill significantly improved obstructive sleep apnea (OSA) symptoms in a large phase 3 clinical trial presented at the 2026 ATS International Conference. [...]

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One company may know everything about you

The American Prospect: “The world’s largest advertising conglomerate has proposed merging with the company that has built detailed profiles on every American. A disturbing story at the intersection of innovations in war and our surveillance economy broke last week. Reuters reported on a letter sent by U.S. Central Command to Sen. Ron Wyden (D-OR) back ...

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No Vaccine No Problem: Papua New Guinea Malaria Deaths Fall by 92%

Using only current methods of prevention, testing, and treatment, Papua New Guinea has reduced the rate of malaria deaths from 13 per 100,000 inhabitants to just 1. PNG is responsible for some 90% of all malaria cases in the Western Pacific region. Lucy Dally, the country’s malaria coordinator, presented this incredible drop in the fatality […]

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A global dataset of microplastics in urban stormwater runoff (2018–2024)

Urban stormwater runoff (2018–2024). Sci Data 13, 784 (2026). https://doi.org/10.1038/s41597-026-07137-y. “Microplastic (<5 mm) pollution is a growing environmental concern, with urban stormwater systems serving as critical transport pathways. While microplastics predominantly originate and circulate within urban environments, transported via stormwater runoff to receiving water bodies, existing…

A new drug just cleared hepatitis B in 1 in 5 patients

BY THE OPTIMIST DAILY EDITORIAL TEAM A clinical trial published May 28 in the New England Journal of Medicine reports that a new drug called bepirovirsen achieved a functional cure in approximately one in five patients with chronic hepatitis B. That number matters. The current standard of care achieves a functional cure in around three […]

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US healthcare still stupidly expensive, with pathetic outcomes, study finds

The Commonwealth Fund – U.S. Health Care from a Global Perspective, 2026: “Countries around the world are grappling with the shared challenges of rising health care costs, physician burnout, and aging populations. Yet the United States has long been an outlier in several respects. The U.S., on average, has the poorest health outcomes of any ...

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Health Care Must Serve Patients, Not Corporations

Searchlight Institute: Health Care Must Serve Patients, Not Corporations. May 26, 2026. Too often, the deck is stacked against patients and individual health care providers trying to do the right thing for the patients, because corporations dominate the health care marketplace and put profits first. Costs rise, care is denied, and patients are too often ...

Two drug molecules achieve myelin repair in MS disease models

BY THE OPTIMIST DAILY EDITORIAL TEAM Every remyelination drug candidate tested in multiple sclerosis research has failed. A doctoral thesis from the University of Helsinki, defended earlier this month, reports two that didn’t. Tapani Koppinen, working in Associate Professor Merja Voutilainen’s research group, identified two separate drug molecules that successfully triggered myelin regrowth in MS…

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Guinea Worm Disease Reaches All-Time Low: Only 10 Human Cases Reported in 2025

Only 10 human cases of Guinea worm were reported worldwide in 2025, the lowest number ever recorded, bringing the ancient disease closer than ever to eradication. Poised to be only the second human disease eradicated after smallpox, the 10 Guinea worm cases mark a 33% decline from the 15 cases reported in 2024. Shared in […]

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These 5 charts show how ChatGPT is flooding our lives

Washington Post [no paywall] – “Self-filed lawsuits. New books. Scientific papers. See the data behind the surge. The impact of ChatGPT on society can be summed up with a single word: more. Since OpenAI’s artificial intelligence tool debuted in late 2022, anyone can rapidly churn out reams of text resembling academic papers, legal documents, poems ...

Chile’s maternity leave expansion led to a three-year employment boost

BY THE OPTIMIST DAILY EDITORIAL TEAM In October 2011, Chile extended postnatal leave from 12 to 24 weeks for women contributing to the country’s social security system. The reform also introduced five days of paid paternity leave. A study published this year by economist Francisca Rojas-Ampuero tracks what happened to women’s employment in the fourteen […]

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Most U.S. doctors are quietly using this AI tool. Few patients know about it

NBC News: “Over the past two years, medical providers across America have quietly embraced a new AI tool called OpenEvidence to help them make clinical decisions, brush up on medical knowledge and even prepare for their licensing exams. The service, a sort of chatbot for doctors, was used by about 65% of U.S. doctors across ...

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Who Paid, and Who Stayed? Early 2026 Enrollment Trends in the Individual Market

“A new report from Wakely Consulting Group, an HMA Company, models changes to the 2026 ACA market enrollment due to the loss of federal subsidies. Findings suggest a larger drop in ACA marketplace enrollment – lower than some feared, but higher than the CBO analysis. Download Full Report – “Based on unique data collection from ...

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RFK Jr.’s department to make it easier to fire career staff

Politico: “The Health and Human Services Department is moving hundreds of senior career staff to a new civil service classification that will make it easier to fire them. President Donald Trump tinkered with the idea late in his first term and the Heritage Foundation, a conservative think tank, recommended the reclassification of career staff with ...

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